Are MAOIs Effective?
Comparative treatment studies have found MAOIs frequently are more effective than several other medication classes including SSRIs and TCAs in treating several conditions including:
- Depression [1-5]
- Anxiety disorders including generalized and social anxiety, panic disorder & more [6-11]
- Bipolar disorder [12-13]
Guidelines from large medical societies support more widespread use of MAOIs given their effectiveness in atypical and treatment-resistant mental health disorders [12-19] with studies reporting a 70% response rate among difficult cases. [20, 21] Due to their high rate of effectiveness among MAOIs, when they fail to produce a sufficient therapeutic response, it is often due to prescriber inexperience. [28-32]